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There are several reasons that the glands that produce saliva, called the salivary glands, might not function properly. These include:
- Side effects of some medications - over 400 medicines can cause dry mouth, including antihistamines, decongestants, pain killers, diuretics and medicines for high blood pressure and depression.
- Disease - diseases that affect the salivary glands, such as diabetes, Hodgkin's, Parkinson's disease, HIV/AIDS and Sjogren's syndrome, may lead to dry mouth.
- Radiation therapy - the salivary glands can be damaged if your head or neck are exposed to radiation during cancer treatment. The loss of saliva can be total or partial, permanent or temporary.
- Chemotherapy - drugs used to treat cancer can make saliva thicker, or "ropey," causing your mouth to feel dry.
- Menopause - changing hormone levels affect the salivary glands, often leaving menopausal and post-menopausal women with a persistent feeling of dry mouth.
- Smoking - many pipe, cigar and heavy cigarette smokers experience dry mouth.
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